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Notably, individuals with inflammatory bowel disease (IBD) have significantly higher MP concentrations in their feces than healthy controls, and these concentrations correlate with disease severity, suggesting that MPs may exacerbate intestinal inflammation by worsening microbial imbalance [79]

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This is when: Most people think "okay, this is actually working." Month 4-6: Significant transformation Physical changes: 5-10 pounds lean muscle gain (cumulative) 15-25% strength increases across all lifts Substantial improvement in body composition Fat loss continues even while building muscle Muscle maturity - look more "filled out" What you'll notice: Completely different physique Clothes fit differently (tighter upper body, looser waist) Consistent comments from friends and family Training weights significantly higher than starting point Visible abs even if they weren't there before (if diet is decent) What photos show: This is where dramatic before and after photos come from

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