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Metabolite-mediated PTMs of proteins undoubtedly play a vital role in tumor cells, affecting both histones and non-histone proteins, covering modifications such as lactylation, crotonylation, acetylation, palmitoylation, and succinylation
For example, acetaminophen (commonly recognized as Tylenol) toxicity is the common cause of medication-induced hepatotoxicity
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The divergent roles of dietary saturated and monounsaturated fatty acids on nerve function in murine models of obesity
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