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although in some cases, the macules may be confused for melanoma in situ (a precancerous skin condition) In a majority, no treatment of Melanotic Macules of Oral Mucosa may be necessary and the healthcare provider may undertake a wait and watch approach In case treatment is necessary, it may be provided and the prognosis is excellent

Glutathione is thought to influence pigmentation by: Inhibiting tyrosinase activity Shifting melanin production from eumelanin to pheomelanin Because of this, it is used for skin lightening in some settings

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These genes contribute to WAT browning by increasing energy expenditure in adipose tissue and by increasing mitochondrial synthesis