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In addition, F336, I343, and I344 in 5 and L194 in 2-3 loop of G i pack against GHSR residues P148 and I149 in ICL2 to form another set of hydrophobic interactions at the receptor and G i interface (Fig

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Characteristics of wave fronts during ventricular fibrillation in human hearts with dilated cardiomyopathy: role of increased fibrosis in the generation of reentry