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A potential biomarker for fatigue: Oxidative stress and anti-oxidative activity

The four-pathway model therefore targets appetite (GLP-1 and amylin through separate neuronal circuits), fat metabolism (GIP and glucagon), energy expenditure (glucagon primarily), and glucose homeostasis (GLP-1, GIP, and amylin all contribute through different mechanisms)

Elevated biomarkers alone do not diagnose disease, and normal biomarkers do not exclude functional impairment

Supplementation of the culture medium with LC during the in vitro maturation of the oocytes favored the acquisition of competence for development, as it improved cytoplasmic and nuclear maturation and reduced ROS levels in the culture medium, showing an antioxidant effect [102]

Retrieved 18 August 2025