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In a frequently cited 1999 rat wound study in the Journal of Investigative Dermatology, topical Thymosin Beta-4 was associated with a 42% increase in reepithelialization at four days and as much as 61% at seven days compared with saline controls, alongside increased angiogenesis

Growth hormone then causes the liver to secrete hormones like insulin-like growth factor 1 (IGF-1), which promotes cell growth and tissue repair, and supports longevity

In the regeneration stage, the fibroblasts (the cells that build the fibers of the connective tissues) proliferate and produce collagens and glycoproteins to form the new tissues

Dose-Response Relationships In animal stroke models, gene expression changes occurred 1-24 hours post-administration, but whether similar timing applies to psychiatric effects is unknown