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This is typically the final stage of testing before a drug can be submitted for regulatory approval
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This does not mean they cannot be combined, but it means researchers should be aware of the additive potential and monitor accordingly
Zelniker TA, Wiviott SD, Raz I et al (2019) Comparison of the effects of glucagon-like peptide receptor agonists and sodiumglucose cotransporter 2 inhibitors for prevention of major adverse cardiovascular and renal outcomes in type 2 diabetes mellitus
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