Methods Data from 4467 adults with type 2 diabetes in the Diabetes Patient Follow-up (DPV) registry were analysed, focusing on changes in HbA 1c and body weight over 6 months following initiation of a GLP-1 RA
Because GLP-1 RAs show significant benefits, especially for high-risk patients with severe circulation problems in their legs, clinicians should consider prescribing GLP-1s because peripheral artery disease, also known as PAD, has limited treatment options, said study author Aravinda Nanjundappa, M.D., an interventional cardiologist in the invasive & interventional cardiology section in the Robert and Suzanne Tomisich Department of Cardiovascular Medicine at the Cleveland Clinic in Cleveland
Starting low is not conservative
In vitro and in vivo experiments in OA, RA and psoriasis models have demonstrated weight-loss-independent anti-inflammatory and chondroprotective effects of GLP-1RAs, commonly through inhibition of the NF-B pathway
But the long-term success comes from learning how to nourish your body in a way that feels doable, flavorful, and sustainable
