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In Alzheimers disease models, spine loss in the hippocampus is one of the earliest and most consistent pathological findings
R.ShunmugiahK
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While previous research has firmly established its capacity to ameliorate hepatic steatosis, likely by activating the hepatic AMPK signaling pathway to promote fatty acid oxidation and inhibit lipogenesis, and exerting anti-inflammatory effects by suppressing cytokines such as TNF- and IL-6 16 , the present study provides a more unified mechanistic explanation for this
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