doi: 10.3389/fmicb.2026.1787284 Received 15 January 2026 Revised 23 February 2026 Accepted 25 February 2026 Published 17 March 2026 Volume 17 - 2026 Edited by Charalampia Amerikanou, Harokopio University, Greece Reviewed by Marie-Joelle Franoise Virolle, Centre National de la Recherche Scientifique (CNRS), France Peng Li, Northwestern Polytechnical University, China Updates Copyright 2026 Niu, Wang, Lu and Yu
Ethics declarations The authors declare no conflict of interest in financial or any other sphere
Joint & Tendon Integrity Models Several studies explore the peptides ability to stimulate: tendon fibroblast outgrowth ligament healing behaviour collagen type I synthesis This makes it of high value in orthopedic research environments
Dorsomedial hypothalamus GLP-1R are known to be expressed in the neurons of the DMH of mice and humans, and previous studies have emphasized its role in regulating metabolic responses by exendin-4 [68,69]
The half-life remains about one week, and the clearance window is still about five to seven weeks for most patients