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Net content assay : AAA or UV-HPLC against reference

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All relevant data are available from the authors upon request and/or included in the manuscript or Supplementary information

The ECM is mainly composed of structural proteins such as basement membrane (BM), collagen, elastin, osteopontin (OPN), and non-structural matrix cellular proteins such as cysteine-rich (Sparc) ( via integrins (30, 31)