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1 Poor prognostic signs include multi-organ failure, which may involve cerebral edema, renal failure, profound hypoglycemia and lactic acidosis, any signs of which should prompt an immediate liver transplant evaluation

Adults over 60 require lower starting doses, pre-treatment cancer screening, glucose monitoring, and more frequent follow-up than younger patients

Before every use, hold the vial up to a light and visually inspect the contents

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