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Ipamorelin is a synthetic pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) classified as a selective ghrelin/growth hormone secretagogue receptor (GHS-R) agonist

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Future research objectives must concentrate on creating prediction algorithms for appropriate receptor targeting ratios, exploring triple-agonist strategies (GLP-1/GIP/glucagon), and determining long-term safety profiles for multi-receptor therapies

Cells 13:22

Eligibility and inclusion criteria Relevant studies retrieved from the comprehensive search were screened based on the inclusion and exclusion criteria (Table 1)