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Insulinotropin: Glucagon-like peptide I (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas

The following will review recent evidence, including from the FLOW and SELECT trials, disclosing benefits of GLP-1 RAs, with a particular focus on kidney disease progression and cardiovascular benefits in patients with diabetes

In a trial that compared participants taking 0.8, 1.6, and 2.4 grams per kilogram (or 0.36, 0.72, and 1.04 grams per pound) per day, intake above 0.8 grams per kilogram of protein per day resulted in sparing of fat free mass and promotion of body fat loss

I remain open to evidence that any one of these peptides or NAD+ will eventually be shown to provide useful health outcome benefits

Consistency is essential for experiencing its benefits