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The 44% nausea rate reported in Wegovy trials at 2.4mg is a relevant number to know going in

But other first-generation GLP-1s approved for diabetes or obesity, including dulaglutide (Trulicity) and liraglutide (Saxenda), may be sold as generics within the coming year

Notably, the limited number of studies and the reliance on few or single-study estimates restrict statistical power, increase uncertainty, and prevent robust assessment of heterogeneity and publication bias

DOI: 10.1186/s12967-024-05753-z [Google Scholar] Kantreva K, Katsaounou P, Saltiki K, Trakada G, Ntali G, Stratigou T, et al

Wound Repair Regen 2020;28:493505