For any transdermal medication system, proper application typically involves several key steps
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The reduction in adiposity may help protect muscle tissue from muscle wasting, which is often seen in obesity-associated catabolic states [28], in addition, sustained negative energy balance promotes fat loss, but also contributes to lean tissue catabolism
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Historically, covering only these indications would limit the availability of rebates, which discouraged some employers from offering coverage for newer indications unless they also covered the broader obesity indication
