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Yeast infections are not listed as a recognised adverse effect in the Summary of Product Characteristics (SmPC) approved by the Medicines and Healthcare products Regulatory Agency (MHRA), nor in the European Medicines Agency's European Public Assessment Report (EPAR) for Wegovy

Topiramate does not affect cardiovascular parameters but requires attention to hydration and kidney stone prevention

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Access to these detailed protocols helps researchers navigate the balance between aggressive weight loss and healthy body composition

The primers used were: 53 F (AAAGCTAGCGCCACCATGAAGACGATCATCGCCCTGAGC) and 53 R (TTTGGCGCGCCCTAA-GAGCAGGACGCCTGACAAGT), ligating the product into pAAV-hSyn-DIO-EGFP (plasmid from Addgene, 50457, RRID: Addgene_50457) in place of the EGFP in NheI and AscI sites to produce the human GLP1R virus construct (AAV-hSyn-DIO-hGLP1R)