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In June 2025, MBX Biosciences announced that it has submitted an IND application to the FDA for MBX 4291, a long-acting GLP-1/GIP receptor co-agonist prodrug targeting obesity, which received regulatory clearance in July

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GLP-1 medications like Ozempic, Wegovy, Mounjaro, and Zepbound have become powerful tools for treating type 2 diabetes and obesity

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