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Overall the risks are small and for many probably dont outweigh the benefits

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The many types of intranasal nanoparticles being developed (polymeric, solid lipid, microemulsions and nanoemulsions, polymeric micelles, nanonstructured lipid carriers, polymer-lipid hybrid, chitosan and PGLA nanoparticles) speak to the richness of this drug delivery field

These medications include GLP-1 receptor agonists like semaglutide (Ozempic, Wegovy, Rybelsus) and liraglutide, as well as dual GIP/GLP-1 receptor agonists like tirzepatide (Mounjaro, Zepbound)