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These niclosamide solution concentrations are 10x to 150x above the in vitro inhibition of SARS-CoV-2 viral replication as measured to date in Vero 6 and Calu-3 cells of 1M 3M (6, 34, 49)

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The strongest evidence remains in topical applications, while injectable GHK-Cu should be viewed as an investigational compound with unknown safety profiles