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semaglutide in direct comparison The clearest head-to-head trial between the two approved molecules for obesity is SURMOUNT-5 (Aronne et al., NEJM 2024, NEJMoa2416394)

Dose reduction strategies After maintaining goal weight for 6 to 12 months at a given dose, some individuals successfully transition to lower maintenance doses

Those without such a diagnosis may find insurer coverage limited, highlighting the importance of understanding both Mounjaro's role solely in diabetes and Zepbound's weight management focus

Contact a healthcare provider if you experience: persistent vomiting or dehydration severe abdominal pain signs of pancreatitis symptoms of gallbladder problems Both medications also carry a boxed warning related to thyroid tumors seen in animal studies, though this has not been confirmed in humans

References [1] A, Lene Jensen , et al