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Response: We appreciate the commenters for their support of ASM's performance assessment framework

"This represents a discrepancy of [redacted] units (approximately [redacted] vials) between the amount of Botox indicated in your purchase records and the amount of product administered to patients," the agency added

The target is 90g or more of daily protein with two to three resistance training sessions per week

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In contrast, fetal muscle showed no changes in mitochondrial activity but displayed reduced expression of genes involved in fat metabolism and energy production, suggesting early transcriptional changes that could affect postnatal muscle energy utilization (Safain et al., 2025)