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These protective effects are attributed to the antioxidant capacity of PRP and growth factors such as IGF-1, which help maintain acrosomal protein integrity and reduce cryodamage [82]

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Meanwhile, M2 macrophages-derived extracellular vesicle (EVs) could also convert activated M1 macrophages into M2 macrophages through in situ macrophage reprogramming and producing a distinct protein expression pattern characteristic of anti-inflammatory M2 macrophages

doi: 10.3181/00379727-107-26644 215 AskarMAEl-SayyadGSGuidaMSKhalifaEShabanaESAbdelrahmanIY

however, specialized bottles and nipple systems exist that facilitate effective nutrition