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Moisturizer: Follow up with a moisturizer that supports your skin barrier (look for ingredients like ceramides, niacinamide, and hyaluronic acid)

Nicotine reduction, in turn, has direct implications for periodontal treatment outcomes and implant candidacy

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The second concerns endpoints: a program built around biomarker movement needs a clear, pre-specified theory of how that biomarker connects to clinical benefit, and a plan for what a divergence would mean