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Total Y-BOCS scores The results indicated a trend toward the beneficial impact of NAC on total Y-BOCS scores over a duration of 12 weeks or longer (MD = -1.87, 95% CI: [-5.39, -1.66], p-Value = 0.30, I 2 = 70%) ( Figure 3 ) ( Figure 4 ), while not significantly effective for four weeks or less (MD = 0.74, 95% CI: [-2.27, 3.74], p-Value = 0.63, I2 = 0%) ( Figure 5 )

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Change of antioxidant enzyme activities, some metals and lipid peroxidation in Alzheimer's disease

Updated analyses from the HEALEY ALS Platform Trial suggest a notable reduction in the risk of death in reviewed populations, alongside a favorable safety profile across more than 1,000 patient-years of exposure