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it's the "other stuff." Many cheaper supplements contain synthetic fillers, artificial flavors, or flow agents like magnesium stearate that can irritate the gut

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Understanding Cholesterol Metabolism CHRIS MASTERJOHN: Yeah

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In addition, the brain is susceptible to oxidative stress because its high in fat, which can oxidize or go rancid. The brain is also high in iron and zinc, which can further fuel oxidative stress