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A lack of cardiac remodeling (as measured by posterior wall thickness [LVPWd] [hypertrophic remodeling] or internal dimension [LVIDd] [LV dilation]) and no change in left ventricular ejection fraction (LVEF) (Fig

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Tirzepatide is presently being examined in a clinical trial (NCT04847557) for patients with moderate HF (NYHA class II-IV) with HFpEF [54]