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Rushworth and Megson, 2014

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With regard to depression, we have few and inconclusive studies, although we would like to point out that one study on patients with a major depressive episode, who had a chronic psychiatric disorder (on average, for almost 17 years) and therefore had a poor response to pharmacological treatment, concluded that supplementing standard treatment with NAC has favorable effects by reducing symptoms and improving patients functioning [129]

Importantly, cerebellar Purkinje neurons exhibited reduced excitability under electrophysiology and altered action potential waveforms, implying modifications in Na + and K + channel expression or function

Wells Fargo reported total annual revenue of about $83.7 billion in 2025 , with modest year-over-year growth driven by net interest income and rate dynamics