glp 1 drugs in development Emerging Trends the of GLP-1 Receptor Agonists Trends in the Development of

Individuals with risk factors for B12 deficiency including strict vegans, those with gastrointestinal conditions, patients taking long-term metformin or proton pump inhibitors, and older adultsshould discuss screening with their GP, even in the absence of obvious symptoms

References: [1] Mendoza Mar Y, Fernndez Mayola M, Aguilera Barreto A, Garca Ojalvo A, Bermdez Alvarez Y, Mir Bentez AJ, Berlanga Acosta J

One such piece of research is a 2020 review published in the journal Nutrients (1)

Moreover, we show BB is the major gut microbial metabolite formed from dietary L -carnitine in mice, and like dietary L -carnitine, in a gut microbiota-dependent manner is converted into TMA and TMAO, and accelerates atherosclerosis

The findings suggest that dysregulation in the excitatory neurotransmission, potentially involving an increased cycling of the Gln-Glu circuit, may contribute to the pathophysiology of ASD