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Wan et al 2017: Impact of compound hypertonic saline solution on decompensated heart failure This is a single-center unblinded RCT in China involving 264 patients with systolic heart failure and refractory volume overload

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improving microbiome diversity may reduce the central sensitisation that makes tinnitus persistent [1, 2] Citable Takeaways A 2025 Mendelian randomization study confirmed causal relationships between gut microbiome composition and tinnitus risk

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