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Recent experimental and clinical observations [15, 19, 23] hint at GLP-1RAs acting as modulators of neuroinflammation, oxidative stress, and neurogenesis, providing a broader framework for their potential impact on psychiatric conditions

To substantiate the weight-lowering efficacy in another rodent species, Sprague-Dawley rats fed a high-fat high-sugar diet for 4 weeks were treated with once-daily s.c

In 2025, Novo Nordisk submitted Orforglipron for regulatory review by the FDA, but it is not yet approved

Diabetologia 66 (10), 18201831