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While effective for diabetes and obesity, semaglutide may cause joint pain through inflammation, blood sugar changes, weight loss, and cartilage effects

68,69 This overactivation of NAD+-consuming pathways with age and disease can severely compromise NAD+ availability in cells, subsequently limiting utilization of NAD+ by other critical NAD+-dependent enzymes that promote good health, such as the SIRTs

This powerful antioxidant also provides additional wellness benefits, such as detoxification and immune support

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