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The mechanism of this pathway requires a high concentration of glucose which is then converted to sorbitol by utilizing the enzyme Aldose reductase requiring coenzyme NADPH oxidized to NADP + (Yan 2018)

It plays a crucial role in numerous biological processes including detoxification, immune function, and cellular repair

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In a 2018 study, male Wistar rats were either given one of two reishi extracts (150mg/kg and 300mg/kg) or one of two placebos (sildenafil and distilled water) to evaluate the mushrooms aphrodisiac potential

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