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Current studies show Melanotan 1 increases melanin synthesis through melanocortin receptor activation, which may enhance photoprotection in research models

Melatonin improves ischemia-induced circulation recovery impairment in mice with streptozotocin-induced diabetes by improving the endothelial progenitor cells functioning

2: Beck DE, Sweeney WB, McCarter MD

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The MHRA update is simply a reminder that powerful drugs require powerful vigilance, and until we have larger, long-duration real-world safety data, clinicians should err on the side of specificity in monitoring and patients should be taught exactly what to look for. Hector Perez, MD