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The relative fluidization of G3BP condensates and increased mobility of G3BP upon addition of ASPL in vitro contrasts with the increased mobile fraction of G3BP observed in cells upon ASPL knockdown, highlighting the complex regulatory mechanisms governing G3BP condensation and mobility in different contexts

Choosing the right diluent is therefore not a side detail it is part of the experimental design

Retinal detachment and injury recovery Mechanism: Physical separation of retina from underlying RPE and choroid, cutting off blood supply and causing photoreceptor death within hours to days

For example, the increased dosage of CBS and GCS in our simulation of Down syndrome causes the intracellular concentration of cysteine to decline while the blood concentration increases

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