In the pathological progression of PD, the impairment of the bloodbrain barrier function may lead to persistent disorders in brain iron homeostasis, thereby further promoting the development of PD
In a physical dependence assay (assessed at 6, 14, 42, and 72 hours after the conditioning treatment) shorter pre-convulsive latencies were noted in diazepam conditioned mice than in non-conditioned healthy mice following an isoniazid treatment forty-two and seventy-two hours after the conditioning treatment
To address this gap, analyzing key drivers of MDVs could elucidate how their biogenesis is upregulated in response to altered energy metabolic conditions, which merits further investigation
33,34,35,36 However, it remains unclear which of the endocrine irAEs are predominantly responsible for such outcomes
2024;16(3): e55378