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*Correspondence: Yongping Liu, [email protected] These authors have contributed equally to this work and share first authorship This article was submitted to Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders, a section of the journal Frontiers in Immunology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Microsomal triglyceride transfer protein (MTTP), an abundant protein in ADSC-Exos, mitigates lipid ROS accumulation through the PRAP1/ZEB1/GPX4 signaling pathway

Polymeric nanoparticles (e.g., PLGA) can improve solubility and exposure with strong regulatory precedent, but degradation-driven release may be less programmable for multi-trigger redox logic ( A pragmatic decision rule is as follows: choose MSNs when the primary requirement is architectural control over interfacial redox kinetics (stability + conditional release) and when a safety/reproducibility package can be credibly assembled

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This correlation was lost upon reoxygenation, however, as the NADP pool was rapidly reduced, while both Grx1-roGFP2 and roGFP2-Orp1 reported a burst in oxidation (Fig