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Regarding GLP-2, Gu and colleagues evaluated a modified GLP-2 analog in mice, demonstrating that it reduced disease severity by restoring epithelial junctions and barrier integrity (72)
The previous reports of multiple beneficial effects of orally administered d-allulose prompted us to infer that it might act through stimulating GLP-1 release and/or vagal afferent signaling, both of which transmit gut signals to remote organs including the brain
K+ efflux agonists induce NLRP3 inflammasome activation independently of Ca2+ signaling
In addition, L-carnitine improves the conditions of the heart, blood vessels and kidneys
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