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13 See FIGURE 1 for a summary of current recommendations from the ADA for second-line therapy in patients with T2DM

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Discussion To the best of our knowledge, this is the first mechanical study showing that NRTP itself impairs ovarian function in multiple ways through pro-inflammatory plasma cytokine binding to an ovarian receptor

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In a recent in vitro study using human prostate cancer cell lines DU145 and PC3, periprostatic adipose tissue promoted prostate cancer resistance to the chemotherapy drug docetaxel through a mechanism involving paracrine IGF-1 upregulation of the -tubulin isoform of tubulin Beta 2B Class IIb (TUBB2B) gene (31)