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This high selectivity allows for more targeted therapeutic effects, often with fewer off-target interactions and a reduced risk of systemic side effects

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Although rare, adverse effects of high-dose vitamin B12 have been reported, including allergic reactions such as fever, rash, itching, hot flushes, dizziness, and nausea, across all cobalamin forms and administration routes (Caballero et al., 2007)

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But eventually they did and the prohormone and designer stimulant holes that existed previously in sport drug testing were closed