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In a Phase 2a trial, GSBR-1290 resulted in a significant weight loss of 6.2% after 12 weeks, outperforming the placebo group

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Molecular interaction studies

Annaliesa Anderson, Pfizers senior vice president and head of vaccine research and development, touted the benefits of Penbrayawhich combines components from two other meningococcal vaccines, Trumenba and Nimenrixsaying the new vaccine has the potential to protect more adolescents and young adults from this severe and unpredictable disease by providing the broadest meningococcal coverage in the fewest shots. Approval for Penbraya was granted based on positive results from Phase II and III trials, including a Phase III study that sought to determine the immunologic noninferiority of the vaccine against meningococcal vaccines currently available in the U.S

Chronic GI inflammation with no clear diagnosis: a standard GI workup came back negative, but bloating, food sensitivity, and discomfort persist