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In the case of pronounced absorption disorders, for example as a result of gastritis or after removal of the small intestine, in Crohn's disease, diverticulosis and the so-called blind-loop syndrome, there is a gradual decrease in the vitamin B12 store in the liver, which can turn into a manifest vitamin B12 deficiency

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But they cannot be used in research until they are dissolved into a precise liquid volume

Rarely, low blood sugar, kidney problems, allergies, increased heart rate and depression or thoughts of suicide may occur

Therefore, exploring the combined application of NNMTi with other interventions has become a research hotspot in recent years