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The activity of these reabsorption proteins depends essentially on the gene expression of certain regions of the DNA

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Cancer cells supplemented with selenium (30 nM sodium selenite or 10 M SeMet) showed elevated levels of GPX1 and TXNRD1 enzyme activity, effectively protecting against DNA strand breaks induced by ultraviolet A- or H 2 O 2 -induced oxidative stress 135

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Except for the levels of IGF-IR, the IGF-activated gene transcription signature is strongly associated with poor prognosis in breast cancer patients [38]