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156 Spermidine, a polyamine that enhances autophagic flux, improves insulin resistance and gut health in preclinical models, although its translational potential remains limited by the lack of robust human data

I've heard it can spoil or degrade into a harmful by-product

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But robust, high-quality evidence for durable cosmetic skin-lightening from IV glutathione is lacking, and the FDA has not approved glutathione for skin lightening