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The breakdown products of BCAAs can be used to form the amino acid glutamate, which can scavenge toxic ammonia in skeletal muscles and convert it into glutamine (Dam, Ott 2013

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Neuroprotective and Abstinence-Promoting Effects of Acamprosate Elucidating the Mechanism of Action Philippe De Witte John Littleton Philippe Parot George Koob Acamprosate is an abstinence-promoting drug widely used in the treatment of alcohol dependence but which has a mechanism of action that has remained obscure for many years