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Furthermore, sertraline has low affinity towards cholinergic, histaminergic, and noradrenergic receptors, causing minor cardiovascular and sedative effects [22]

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For example, research has shown that chemotherapy agents can promote hypoxia in the TME, which drives the activation of hypoxia-inducible factors (HIFs), in particular HIF-

Taken together, the experimental findings discussed above reveal a complex interplay between alcohol-induced zinc deficiency and two fundamental signaling pathways that are required for strong host immune capacity within the alveolar macrophages