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In the brain of children with ASD, low levels of mitochondrial glutathione, mitochondrial dysfunction, oxidative stress and oxidative damage to macromolecules such as lipids, proteins and DNA have been reported (Nathan and Cunningham-Bussel, 2013

While melanocyte stem/progenitor cells and their reservoir niche have been identified in the skin, in the oral mucosa they have not been found [6, 15]