In some cases, investigation may be warranted to exclude other causes of digestive symptoms, such as Helicobacter pylori infection , small intestinal bacterial overgrowth (SIBO), or other gastrointestinal conditions
For context, the weight loss timeline shows what to expect at various dose levels
As patients tolerate these side effects well, the dosage is gradually increased to achieve more noticeable changes in appetite and weight loss
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The dual mechanism produces stronger appetite suppression, greater metabolic improvements , and more significant weight loss outcomes in clinical trials compared to single-receptor drugs