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Annu Rev Cell Dev Biol (2011) 27:44164

Additionally, the metabolic changes associated with significant weight loss and improved glycemic control may temporarily affect energy levels as the body adapts to a new physiological state

Catalase (CAT), an enzymatic scavenger, removes intracellular H 2 O 2 , protecting cells from H 2 O 2 toxicity

Farrand AQ, Gregory RA, Scofield MD, Helke KL, Boger HA (2015) Effects of aging on glutamate neurotransmission in the substantia Nigra of Gdnf heterozygous mice