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Author: Michelle Liu, MPH (No change) Medical Reviewer: Kristen Fuller, MD (No change) Primary Changes: Reviewed entire article and revised where necessary to improve factual accuracy, clarity, and enhanced readability
Reduced lean body composition during weight loss efforts
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Mechanistically, C3G activated the PPAR/--catenin-TCF-4 pathway in STC-1 cells, enhancing PG precursor transcription and GLP-1 synthesis.Inhibiting PPAR/ with GSK0660 blocked this C3G-induced upregulation